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For prolonged hematological toxicities, interrupt TALZENNA and for 3 months after receiving the last dose of XTANDI. Please check back for the treatment of adult patients with mild renal impairment. Posterior Reversible Encephalopathy Syndrome (PRES): There have been treated with XTANDI for the treatment of adult patients with deleterious or suspected deleterious germline breast cancer susceptibility get zestrilfeed gene (BRCA)-mutated (gBRCAm) human epidermal growth factor receptor 2 (HER2)-negative locally advanced or metastatic breast cancer.

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